klb (R&D Systems)
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R&D Systems
klb
Klb, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+klb/Human+Klotho+beta+Antibody/pm41752116-173-8-14
Average 94 stars, based on 15 article reviews
Klb, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+klb/Human+Klotho+beta+Antibody/pm41752116-173-8-14
Average 94 stars, based on 15 article reviews
klb - by Bioz Stars,
2026-09
94/100 stars
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other:Article Title: Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8 + T cells. Article Snippet: In brief Tumor-infiltrating T cells exhibit dysfunction.. Hu et al. report that tumorsecreted FGF21 augments cholesterol production by sustaining the hyperactivation of mTORC1 in activated CD8T cells, consequently inducing T cell exhaustion and impairing CD8T antitumor function.. FGF21 blockade improves anti-tumor immunity, highlighting FGF21 as a potential therapeutic target for cancer immunotherapy. Article Title: FGFR redundancy limits the efficacy of FGFR4-selective inhibitors in hepatocellular carcinoma Article Snippet: The following antibodies were used: anti-Flag–HRP (Sigma-Aldrich, A8592; 1:5,000), anti-FGFR1 (Cell Signaling Technology, 9740; 1:1,000), anti-FGFR3 (Cell Signaling Technology, 4574; 1:1,000), anti-FGFR4 (Cell Signaling Technology, 8562; 1:5,000), Article Title: FGFR redundancy limits the efficacy of FGFR4-selective inhibitors in hepatocellular carcinoma. Article Snippet: The following antibodies were used: anti-Flag–HRP (Sigma-Aldrich, A8592; 1:5,000), anti-FGFR1 (Cell Signaling Technology, 9740; 1:1,000), anti-FGFR3 (Cell Signaling Technology, 4574; 1:1,000), anti-FGFR4 (Cell Signaling Technology, 8562; 1:5,000), Article Title: Sodium sulphate ameliorates hypercholesterolemia via the upregulation of Cyp7a1 in hepatocytes and alleviates hepatic insulin resistance via the downregulation of Trib3 in mice with high cholesterol diets. Article Snippet: The primary antibodies comprised: Rabbit anti‐GaPDH (1:1,000; cat. no. 2118S; CST Biological Reagents Co., Ltd.), mouse anti‐CYP7A1 (1:1,000; cat. no. 2683295; MilliporeSigma), rabbit anti‐hydroxy‐δ‐5‐steroid dehydrogenase, 3 β‐ and steroid δ‐isomerase 7 (HSD3B7; 1:1,000; cat. no. ab190223; abcam), rabbit anti‐aldo‐keto reductase family 1 member D1 (aKR1D1; 1:1,000; cat. no. ab101393; abcam), rabbit anti‐acyl‐Coa oxidase 2 (1:1,000; cat. no. ab197808; abcam), rabbit anti‐hydroxysteroid 17‐β dehydrogenase 4 (HSD17B4; 1:1,000; cat. no. ab97971; abcam), rabbit anti‐CYP27a1 (1:2,000; cat. no. ab126785; abcam), rabbit anti‐CYP39a1 (1:1,000; cat. no. ab129334; abcam), rabbit anti‐isopentenyl‐diphos‐ phate δ isomerase 1 (iDi1; 1:3,000; cat. no. ab97448; abcam), rabbit anti‐lanosterol synthase [anti‐oxidosqualene‐lanosterol cyclase (oSC); 1:1,000; cat. no. ab80364; abcam], rabbit anti‐farnesyl diphosphate farnesyltransferase 1 (FDFT1; 1:1,000; cat. no. ab195046; abcam), rabbit anti‐farnesyl diphosphate synthase (FDPS; 1:2,000; cat. no. ab153805; Abcam), rabbit anti‐mevalonate diphosphate decarboxylase (MVD; 1:1,000; cat. no. ab96226; abcam), rabbit anti‐meva‐ lonate kinase (MVK; 1:1,000; cat. no. ab154515; abcam), rabbit anti‐3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR; 1:1,000; cat. no. ab174830; abcam), rabbit anti‐low density lipoprotein receptor (lDlR; 1:1,000; cat. no. ab52818; abcam), rabbit anti‐c‐Jun n‐terminal kinase (JnK; 1:1,000; cat. no. 9252s; CST Biological Reagents Co., ltd.), mouse anti‐phosphorylated (p)‐JnK (1:2,000; cat. no. 9255s; CST Biological Reagents Co., Ltd.), rabbit anti‐p‐insulin receptor substrate 1 (p‐iRS1; Tyr608) mouse (1:1,000; cat. no. 09‐432; MilliporeSigma), rabbit anti‐iRS‐1 (1:1,000; cat. no. 2382S; CST Biological Reagents Co., Ltd.), rabbit anti‐p‐AKT (Ser473) (1:1,000; cat. no. 4060S; CST Biological Reagents Co., ltd.), rabbit anti‐aKT (1:1,000; cat. no. 4685S; CST Biological Reagents Co., ltd.), mouse anti‐tribbles pseudokinase 3 (TRB3; 1:100; cat. no. sc‐390242; Santa Cruz Biotechnology, inc.), rabbit anti‐c‐Jun (1:1,000; cat. no. ab32137; abcam), mouse anti‐p‐c‐Jun (1:200; cat. no. sc‐822; Santa Cruz Biotechnology, inc.) and goat |
